Quantitative gene expression assessment identifies appropriate cell line models for individual cervical cancer pathways-6

<p><b>Copyright information:</b></p><p>Taken from "Quantitative gene expression assessment identifies appropriate cell line models for individual cervical cancer pathways"</p><p>http://www.biomedcentral.com/1471-2164/8/117</p><p>BMC Genomics 2007;8():117-117.</p><p>Published online 10 May 2007</p><p>PMCID:PMC1878486.</p><p></p>an organotypic environment (white). There were more pathways with a higher correlation to cervical cancer in the organotypic culture than in monolayer (p < 0.004, t-test). Therefore, organotypic cultures were better models of cervical cancer than simple monolayer cultures. B: In the ''Cell-Cell Signaling'' pathway (GO:7267), HeLa cells cultured in an organotypic culture had a higher correlation to both normal cervix and cervical cancer than either monolayer or organotypic control cultures