Collagen Type I (μg) measured by ELISA in LAD fibroblasts treated with 10M testosterone or 10M estrogen

<p><b>Copyright information:</b></p><p>Taken from "A cell culture model using rat coronary artery adventitial fibroblasts to measure collagen production"</p><p>http://www.biomedcentral.com/1471-2261/7/13</p><p>BMC Cardiovascular Disorders 2007;7():13-13.</p><p>Published online 8 May 2007</p><p>PMCID:PMC1885448.</p><p></p> Testosterone significantly increased the amount of collagen deposited (2.912 ± 0.247 μg) compared to control values (2.475 ± 0.211 μg) (* p < 0.05, 1 tailed t-test). Estrogen decreased the amount of collagen (2.103 ± 0.262 μg) compared to control (p = 0.058, 1 tailed t-test). Collagen was measured in wells with a 0.32 cmgrowth area from a 96 well culture plate