Correlation between the siRNA efficacy in cell and values relevant to siRNA local duplex stability from position 1 to 18 in the antisense strand

<p><b>Copyright information:</b></p><p>Taken from "Comparison of approaches for rational siRNA design leading to a new efficient and transparent method"</p><p></p><p>Nucleic Acids Research 2007;35(8):e63-e63.</p><p>Published online 10 Apr 2007</p><p>PMCID:PMC1885645.</p><p>© 2007 The Author(s)</p> values were calculated for each of two neighboring base pairs in siRNA duplexes starting from the 5′ end of the antisense strand. siRNA efficacy values were measured as remaining levels of mRNA or normalized protein products levels. Only correlation coefficients that are significant