Regulation of CD36 mRNA expression by tumor necrosis factor (TNF)α and adalimumab

<p><b>Copyright information:</b></p><p>Taken from "Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes"</p><p>http://arthritis-research.com/content/9/2/R22</p><p>Arthritis Research & Therapy 2007;9(2):R22-R22.</p><p>Published online 2 Mar 2007</p><p>PMCID:PMC1906797.</p><p></p> TNFα decreases CD36 mRNA expression and adalimumab increases CD36 mRNA expression. Human monocytes were incubated with macrophage-serum-free medium (M-SFM) alone (control), or with M-SFM containing TNFα (10 ng/ml) or adalimumab (Ada; 1 μg/ml) for 4 h. CD36 mRNA expression was quantified using RT-PCR and normalized to β-actin. Data represent the mean ± standard error of the relative quantification of CD36 mRNA expression measured in three experiments. *Significantly different from control (< 0.05)