The laminar structure of null eyes is normal after 5 days of development

<p><b>Copyright information:</b></p><p>Taken from "Pbx homeodomain proteins pattern both the zebrafish retina and tectum"</p><p>http://www.biomedcentral.com/1471-213X/7/85</p><p>BMC Developmental Biology 2007;7():85-85.</p><p>Published online 16 Jul 2007</p><p>PMCID:PMC1934912.</p><p></p> All laminar layers are present and in both wild type (A and B) and, and mutants injected with morpholinos (D and E). We note a consistent decrease in eye size in null embryos, but the proportion of eye area occupied by the retinal pigmented epithelium in morphants is significantly increased (F verses C). The relative position of the optic nerve is similar in both wild type and morphant embryos. The retinal photoreceptor layer is absent in the ventral domain of the eye in mutants injected with morpholinos (I) when compared to wildtype (G) and is disorganized (compare H, wildtype, with J, mutants injected with morpholinos). Photoreceptor labeling was accomplished using the zpr-1 monoclonal antibody