Tau phosphorylation by GSK-3β promotes tangle-like filament morphology-3

<p><b>Copyright information:</b></p><p>Taken from "Tau phosphorylation by GSK-3β promotes tangle-like filament morphology"</p><p>http://www.molecularneurodegeneration.com/content/2/1/12</p><p>Molecular Neurodegeneration 2007;2():12-12.</p><p>Published online 28 Jun 2007</p><p>PMCID:PMC1936422.</p><p></p>hown in Figure 3, were diluted five-fold and prepared for transmission electron microscopy (TEM). Panels A, C and E show representative clusters of filaments at a magnification of 50,000 × (scale bar represents 500 nm). Panels B, D and F show the same clusters at a magnification of 100,000 × (scale bar represents 100 nm). In the higher magnification micrographs, white arrowheads denote non-touching filaments; white asterisks, branching filaments; and black arrowheads, tendril-like fibrils that appear to laterally connect larger adjacent filaments