The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor-4

<p><b>Copyright information:</b></p><p>Taken from "The binding site for neohesperidin dihydrochalcone at the human sweet taste receptor"</p><p>http://www.biomedcentral.com/1472-6807/7/66</p><p>BMC Structural Biology 2007;7():66-66.</p><p>Published online 12 Oct 2007</p><p>PMCID:PMC2099433.</p><p></p> (B) Representative calcium traces elicited upon stimulation with different concentrations of neohesperidin dihydrochalcone (NHDC) in HEK293T-G16Gust44 cells cotransfected with DNA for hTAS1R2/hTAS1R3. (C,D) Calcium responses of cells cotransfected with DNA for different rat and human subunits or chimeras upon stimulation with 1 mM NHDC (C), or 30 mM D-Tryptophan (D). R, rat receptor subunit; H human receptor subunit; HR, receptor chimera comprising the N-terminal extra cellular domain of the human receptor subunit fused to the corresponding heptahelical domain of the rat; RH, comprising the N-terminal extracellular domain of the rat receptor subunit fused to the corresponding heptahelical domain of the human receptor