A microarray study of gene and protein regulation in human and rat brain following middle cerebral artery occlusion-2

<p><b>Copyright information:</b></p><p>Taken from "A microarray study of gene and protein regulation in human and rat brain following middle cerebral artery occlusion"</p><p>http://www.biomedcentral.com/1471-2202/8/93</p><p>BMC Neuroscience 2007;8():93-93.</p><p>Published online 12 Nov 2007</p><p>PMCID:PMC2194693.</p><p></p>m 2 to 6 days following stroke (Ai) and rats at 3 days after MCAO (Aii). Western blotting demonstrated an increase in protein levels in infarcted and peri-infarcted areas of patients surviving for 29 (Bi) and 26 (Bii) days following stroke. Weak MMP11 staining in cells from contralateral areas of a patient surviving for 5 days following stroke (Ci). Blood vessels (Cii) and neurons (Ciii) strongly stained for MMP11 in peri-infarcted areas of a patient surviving for 15 days after stroke (arrows). No MMP11 staining observed in contralateral hemisphere of rat brain at 1 h after MCAO (Di) but neurons from infarcted areas of rat brain were stained positive for MMP11 at 3 days following MCAO (Dii) (C: Contralateral, P: Peri-infarct, I: Infarct)