<p><b>Copyright information:</b></p><p>Taken from "Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human intervertebral disc: an zymographic and gene therapy study"</p><p>http://arthritis-research.com/content/9/4/R83</p><p>Arthritis Research & Therapy 2007;9(4):R83-R83.</p><p>Published online 30 Aug 2007</p><p>PMCID:PMC2206387.</p><p></p> The graphs show the effects of medium alone, untransfected cells and cells transfected with IL-1Ra on the proportion of nucleus pulposus (NP) cells expressing the various enzymes by NP cells in human IVD explants at 48 hours and 14 days after injection of medium, medium containing non-transfected cells and medium containing trans...
Intervertebral disc degeneration is characterized by a cascade of cellular, biochemical and structur...
Poster PresentationConference Theme: The extracellular matrix nicheBackground and objectives Low ba...
Study Design. In vitro study to develop an intervertebral disc degeneration (IDD) organ culture mode...
Data implicate IL-1 in the altered matrix biology that characterizes human intervertebral disc (IVD)...
Conventional therapies for low back pain (LBP) are purely symptomatic and do not target the cause of...
Degeneration of the intervertebral disc has been implicated in chronic low back pain. Type II collag...
OBJECTIVES: Interleukin 1 (IL-1) is potentially important in the pathogenesis of intervertebral disc...
Introduction: The aim of this study was to compare the effects of tumour necrosis factor-alpha (TNF-...
Objective. To establish if IL-1 or TNF regulates matrix degradation in the non-degenerate or degener...
In this study, we investigated the hypotheses that in human intervertebral disc (IVD) degeneration t...
<p><b>Copyright information:</b></p><p>Taken from "Catabolic cytokine expression in degenerate and h...
Objective: These studies investigated cytokine and chemokine receptor profiles in nucleus pulposus (...
<p><b>Copyright information:</b></p><p>Taken from "Catabolic cytokine expression in degenerate and h...
<p><b>Copyright information:</b></p><p>Taken from "Catabolic cytokine expression in degenerate and h...
ine osteoarthritis (OA) and the inflammatory disease rheumatoid arthritis (RA) are characterized by ...
Intervertebral disc degeneration is characterized by a cascade of cellular, biochemical and structur...
Poster PresentationConference Theme: The extracellular matrix nicheBackground and objectives Low ba...
Study Design. In vitro study to develop an intervertebral disc degeneration (IDD) organ culture mode...
Data implicate IL-1 in the altered matrix biology that characterizes human intervertebral disc (IVD)...
Conventional therapies for low back pain (LBP) are purely symptomatic and do not target the cause of...
Degeneration of the intervertebral disc has been implicated in chronic low back pain. Type II collag...
OBJECTIVES: Interleukin 1 (IL-1) is potentially important in the pathogenesis of intervertebral disc...
Introduction: The aim of this study was to compare the effects of tumour necrosis factor-alpha (TNF-...
Objective. To establish if IL-1 or TNF regulates matrix degradation in the non-degenerate or degener...
In this study, we investigated the hypotheses that in human intervertebral disc (IVD) degeneration t...
<p><b>Copyright information:</b></p><p>Taken from "Catabolic cytokine expression in degenerate and h...
Objective: These studies investigated cytokine and chemokine receptor profiles in nucleus pulposus (...
<p><b>Copyright information:</b></p><p>Taken from "Catabolic cytokine expression in degenerate and h...
<p><b>Copyright information:</b></p><p>Taken from "Catabolic cytokine expression in degenerate and h...
ine osteoarthritis (OA) and the inflammatory disease rheumatoid arthritis (RA) are characterized by ...
Intervertebral disc degeneration is characterized by a cascade of cellular, biochemical and structur...
Poster PresentationConference Theme: The extracellular matrix nicheBackground and objectives Low ba...
Study Design. In vitro study to develop an intervertebral disc degeneration (IDD) organ culture mode...