The cytotoxic and growth inhibitory effects of CDIM9 in MD-MB231 and BT549 cells

<p><b>Copyright information:</b></p><p>Taken from "1,1-Bis(3'-indolyl)-1-(-biphenyl)methane inhibits basal-like breast cancer growth in athymic nude mice"</p><p>http://breast-cancer-research.com/content/9/4/R56</p><p>Breast cancer research : BCR 2007;9(4):R56-R56.</p><p>Published online 31 Aug 2007</p><p>PMCID:PMC2206732.</p><p></p> MDA-MB231 cells, SKMCs, BT549 cells, and HSMMs were treated with serial diluted CDIM9 at between 1 × 10and 1.9 × 10mol/l for 48 hours. The ECvalues were determined using GraphPad Prism software. Cell growth inhibition assay. MD-MB231 and BT549 cells were treated with 1 to 10 μmol/l CDIM9 for 6 days, and cell numbers were determined as described in Materials and methods. Results are expressed as means ± standard error for three separate determinations at each time point. CDIM9, 1,1-bis (3'-indolyl)-1-(p-biphenyl) methane; EC, concentration producing 50% of the maximum possible response; HSMM, human muscle myoblast; SKMC, human skeletal muscle cell