Typical radiographic images obtained on day 28, showing differences in paws

<p><b>Copyright information:</b></p><p>Taken from "IL-23 induces human osteoclastogenesis via IL-17 , and anti-IL-23 antibody attenuates collagen-induced arthritis in rats"</p><p>http://arthritis-research.com/content/9/5/R96</p><p>Arthritis Research & Therapy 2007;9(5):R96-R96.</p><p>Published online 23 Sep 2007</p><p>PMCID:PMC2212562.</p><p></p> The groups were control rats, vehicle-treated rats with collagen-induced arthritis (CIA), and rats with CIA treated with anti-IL-23 antibody on day 28. Frontal views; lateral views. Control rats. Rats with CIA treated with vehicle. Rats with CIA treated with anti-IL-23 antibody (3.0 μg) from day 14. Note that rats wth CIA treated with vehicle showed radiographic changes characterized by bone erosion and joint space narrowing