Detection of short repeated genomic sequences on metaphase chromosomes using padlock probes and target primed rolling circle DNA synthesis-2

<p><b>Copyright information:</b></p><p>Taken from "Detection of short repeated genomic sequences on metaphase chromosomes using padlock probes and target primed rolling circle DNA synthesis"</p><p>http://www.biomedcentral.com/1471-2199/8/103</p><p>BMC Molecular Biology 2007;8():103-103.</p><p>Published online 13 Nov 2007</p><p>PMCID:PMC2212658.</p><p></p>c detection of a 40 nucleotide sequence in the male specific satellite I region on the long arm of the Y-chromosome. Site specific detection of a 32 nucleotide sequence of the kringle IV domain in the gene. It seems that individual rolling circle reactions can produce products long enough to be resolved as threads of DNA in the microscope. Scale bar, 100 μm