Mononuclear cells modulate the activity of pancreatic stellate cells which in turn promote fibrosis and inflammation in chronic pancreatitis-6

<p><b>Copyright information:</b></p><p>Taken from "Mononuclear cells modulate the activity of pancreatic stellate cells which in turn promote fibrosis and inflammation in chronic pancreatitis"</p><p>http://www.translational-medicine.com/content/5/1/63</p><p>Journal of Translational Medicine 2007;5():63-63.</p><p>Published online 5 Dec 2007</p><p>PMCID:PMC2234395.</p><p></p>tin (B; VIM), CD31 (C), CD45 (D), collagen1 (E; COL) and fibronectin (F; FBN). Arrows: area around packed clusters of mononuclear cells. Arrowheads in A-C: pancreatic stellate cells (SMA- and VIM-positive, CD31-negative). Arrowhead in D: loosely distributed area of mononuclear cell infiltration. Arrowhead in E&F: areas of less intense immunoreactivities for collagen1 and fibronectin. Dotted arrows: Areas of strong collagen1 and fibronectin staining. Original magnification: ×50. (G) Arrows: areas of loosely distributed/single mononuclear cells, dotted arrows: area without mononuclear cells. (H&I) Arrows/dotted arrows: corresponding areas to (G)