The androgen receptor can signal through Wnt/β-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens-4

<p><b>Copyright information:</b></p><p>Taken from "The androgen receptor can signal through Wnt/β-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens"</p><p>http://www.biomedcentral.com/1471-2121/9/4</p><p>BMC Cell Biology 2008;9():4-4.</p><p>Published online 24 Jan 2008</p><p>PMCID:PMC2246119.</p><p></p>n normal prostate tissues, the low levels of AR expression, compared with the high levels in prostate cancer cells, were indicated by lack of AR staining in cells (A); β-Catenin was predominantly located at the normal cytoplasmic membrane (B). In late stage prostate cancer samples, AR was substantially overexpressed in the nuclei of the prostate cancer cells (C) where nuclear β-Catenin staining was also observed in some of these cells (D)