Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships-0

<p><b>Copyright information:</b></p><p>Taken from "Bioinformatic analysis of the neprilysin (M13) family of peptidases reveals complex evolutionary and functional relationships"</p><p>http://www.biomedcentral.com/1471-2148/8/16</p><p>BMC Evolutionary Biology 2008;8():16-16.</p><p>Published online 23 Jan 2008</p><p>PMCID:PMC2259306.</p><p></p>s presented. A highly conserved section of the alignment, representing residues 541 to 652 of human neprilysin, contains important catalytic residues. These residues include the HExxH zinc binding motif and the catalytically important GENIAD and VNAFY motifs which are coloured blue. For full alignment see additional file