Tissue-specific requirements for specific domains in the FERM protein Moe/Epb4.1l5 during early zebrafish development-5

In mutants, very little Crumbs protein is visible and ZO-1 labeling is disorganized. (C) In mRNA injected mutants, streaks of panCrb labeling are visible, but an organized OLM is absent. Ultrastructural transmission electron microscopic analysis at 6 dpf in wild-type (D), mutants (E) and mRNA injected mutants (F) retinas. Electron dense outer segments are seen in all individuals. Insets, higher magnifications of rod outer segments showing regular disc stacking is present in all individuals (100,000X). RPE, retinal pigmented epithelium; OS, outer segments; IS, inner Segments; CB, cell body. (A-C) are confocal z-projections, scale bar 10 μm (D-F). Scale bars, 5 μm (D-F), 100 nm (insets).<p><b>Copyright information:</b></p><p>Taken from "Tissue-specific requirements for specific domains in the FERM protein Moe/Epb4.1l5 during early zebrafish development"</p><p>http://www.biomedcentral.com/1471-213X/8/3</p><p>BMC Developmental Biology 2008;8():3-3.</p><p>Published online 11 Jan 2008</p><p>PMCID:PMC2266719.</p><p>