Regulation of mouse gene expression by NF-Y and association of CpG methylation with its tissue-specific expression-8

Tivity is shown as the mean ± SD based on the activity of pGL4 (shown as construct 0) as 1 from three independent experiments, each carried out in duplicate. () Mouse promoter sequence of -600 bp to the transcription start site. Start points of the deletion constructs, -59, -91, -184, -273, and -598 are shown. NF-Y binding 'CCAAT" sites are boxed. PU-boxes are shown in shaded boxes. A STAT binding site previously described for IL-4/13-induced increase of gene expression is shown in black box with white letters. GATA, HNF3β, and C/EBP binding sites identified by low stringency TF search analysis are indicated by over-bracket, overlined and underlined, respectively. CpG methylation sites are indicated in a gray box for complete methylation, and circled for unmethylated sites (see also Fig. 7 and Table 1).<p><b>Copyright information:</b></p><p>Taken from "Regulation of mouse gene expression by NF-Y and association of CpG methylation with its tissue-specific expression"</p><p>http://www.biomedcentral.com/1471-2199/9/5</p><p>BMC Molecular Biology 2008;9():5-5.</p><p>Published online 14 Jan 2008</p><p>PMCID:PMC2266941.</p><p>