() or (). The inner (arrows in -) and outer hair cell regions (brackets in -) are indicated. The arrows in -indicate the layer of supporting cells. () The dynamic expression of in the developing cochlea is schematically diagramed. At E14.5, the expression domain of (grey lines) overlaps with that of (green lines) and p27/Kip1 (black) at its medial and lateral borders, respectively. At E16.5, is expressed similarly to that of (red lines) and (yellow lines) in a subset of supporting cells, while p27/Kip1 is present in all the cells surrounding hair cells (open circles). By E17.5, the expression of has started to be down-regulated from the organ of Corti at the basal region where the expression of remains. Scale bar: 10 μm for -.<p><b>Copyrigh...
The mammalian inner ear contains two sensory organs, the cochlea and vestibule. Their sensory neuroe...
The mammalian cochlea contains an invariant mosaic of sensory hair cells and non-sensory supporting ...
During cochlear development, hair cells (HCs) and supporting cells differentiate in the prosensory d...
() or (). The inner (arrows in -) and outer hair cell regions (brackets in -) are indicated. The arr...
For (,), (,,), (), (), (), and (). Arrowheads in -indicate the domain for sensory and neuronal linea...
For (,), (,,), (), (), (), and (). Arrowheads in -indicate the domain for sensory and neuronal linea...
E18.5, and stained for a hair cell marker, Myosin6. Images from the apical (, , , ), middle (,,,), a...
Ies against p27/Kip1 (,), BrdU (), or doubly stained for Myosin6 and BrdU (-). Brackets in (-) indic...
Lated from animals with the genotypes specified (). The percent of the number of hair cells in extra...
AbstractNotch-mediated lateral inhibition has been reported to regulate auditory hair cell and suppo...
<p>In the cochlea, Hmga2 (shown in blue) is co-expressed with Sox2 (shown in green) expressing-cells...
SummaryThe organ of Corti, the auditory organ of the inner ear, contains two types of sensory hair c...
<p>Tangential section through the mid-turn (z-section) of the cochlea showing widespread expression ...
<p><b>A–D:</b> RNA <i>In situ</i> hybridisation for <i>Bmp4</i> E12.5 in <i>hb/hb</i> and littermate...
<p>(A–C) p27<sup>Kip1</sup> (magenta) is expressed in the post-mitotic, BrdU (green) negative, prose...
The mammalian inner ear contains two sensory organs, the cochlea and vestibule. Their sensory neuroe...
The mammalian cochlea contains an invariant mosaic of sensory hair cells and non-sensory supporting ...
During cochlear development, hair cells (HCs) and supporting cells differentiate in the prosensory d...
() or (). The inner (arrows in -) and outer hair cell regions (brackets in -) are indicated. The arr...
For (,), (,,), (), (), (), and (). Arrowheads in -indicate the domain for sensory and neuronal linea...
For (,), (,,), (), (), (), and (). Arrowheads in -indicate the domain for sensory and neuronal linea...
E18.5, and stained for a hair cell marker, Myosin6. Images from the apical (, , , ), middle (,,,), a...
Ies against p27/Kip1 (,), BrdU (), or doubly stained for Myosin6 and BrdU (-). Brackets in (-) indic...
Lated from animals with the genotypes specified (). The percent of the number of hair cells in extra...
AbstractNotch-mediated lateral inhibition has been reported to regulate auditory hair cell and suppo...
<p>In the cochlea, Hmga2 (shown in blue) is co-expressed with Sox2 (shown in green) expressing-cells...
SummaryThe organ of Corti, the auditory organ of the inner ear, contains two types of sensory hair c...
<p>Tangential section through the mid-turn (z-section) of the cochlea showing widespread expression ...
<p><b>A–D:</b> RNA <i>In situ</i> hybridisation for <i>Bmp4</i> E12.5 in <i>hb/hb</i> and littermate...
<p>(A–C) p27<sup>Kip1</sup> (magenta) is expressed in the post-mitotic, BrdU (green) negative, prose...
The mammalian inner ear contains two sensory organs, the cochlea and vestibule. Their sensory neuroe...
The mammalian cochlea contains an invariant mosaic of sensory hair cells and non-sensory supporting ...
During cochlear development, hair cells (HCs) and supporting cells differentiate in the prosensory d...