He best template (PDB code: ). Blue and red lines represent the backbone of the experimental and template structures, respectively. One bad region is identified. (2) The superimposition of the experimental structure and a good template (PDB code: ). One bad region is identified. (3) The superimposition of the experimental structure and the model generated by 3Dpro during CASP7, based on multiple templates). Two bad regions in (1) and (2) are corrected in the model (3). Most other regions of the model are also closer to the experimental structure than the two templates.<p><b>Copyright information:</b></p><p>Taken from "A multi-template combination algorithm for protein comparative modeling"</p><p>http://www.biomedcentral.com/1472-6807/8/18</...
Protein comparative modelling (CM) is a predictive technique to build an atomic model for a polypept...
of selected SEQ models (empty circles) is shown as a function of SEQ alignment accuracy. The curve f...
Template-based modeling (termed also Comparative or Homology Modeling) of a protein structure is one...
TS scores than the single-template approach. The dots above the line represent the targets where the...
�� -1 Å; or neutral: 1 Å > Δ RMSD > -1 Å. In all plots only models based on template combinations fo...
S2 less than 5%, S1 < 30%, S3 < 30% and template RMSD between 3.5 and 5.5 Å are shown here. The dark...
Roach yields higher GDT-TS scores than the best-template approach.<p><b>Copyright information:</b></...
MOTIVATION: Two major bottlenecks in advancing comparative protein structure modeling are the effici...
Es (top). The Target segment corresponding to the box has no structural information in absence of Te...
Es (top). The Target segment corresponding to the box has no structural information in absence of Te...
<p>(A) Our two-component mixture restraints improve GDT-ha model quality over Modeller’s default res...
Background: Although multiple templates are frequently used in comparative modeling, the effect of i...
Xing and matching between two initial models. The backbone ribbon representations of the experimenta...
Motivation: Modelling the 3D structures of proteins can often be enhanced if more than one fold temp...
T T0368 (PDB identifier ), the refined CF model (red), and the initial comparative prediction (green...
Protein comparative modelling (CM) is a predictive technique to build an atomic model for a polypept...
of selected SEQ models (empty circles) is shown as a function of SEQ alignment accuracy. The curve f...
Template-based modeling (termed also Comparative or Homology Modeling) of a protein structure is one...
TS scores than the single-template approach. The dots above the line represent the targets where the...
�� -1 Å; or neutral: 1 Å > Δ RMSD > -1 Å. In all plots only models based on template combinations fo...
S2 less than 5%, S1 < 30%, S3 < 30% and template RMSD between 3.5 and 5.5 Å are shown here. The dark...
Roach yields higher GDT-TS scores than the best-template approach.<p><b>Copyright information:</b></...
MOTIVATION: Two major bottlenecks in advancing comparative protein structure modeling are the effici...
Es (top). The Target segment corresponding to the box has no structural information in absence of Te...
Es (top). The Target segment corresponding to the box has no structural information in absence of Te...
<p>(A) Our two-component mixture restraints improve GDT-ha model quality over Modeller’s default res...
Background: Although multiple templates are frequently used in comparative modeling, the effect of i...
Xing and matching between two initial models. The backbone ribbon representations of the experimenta...
Motivation: Modelling the 3D structures of proteins can often be enhanced if more than one fold temp...
T T0368 (PDB identifier ), the refined CF model (red), and the initial comparative prediction (green...
Protein comparative modelling (CM) is a predictive technique to build an atomic model for a polypept...
of selected SEQ models (empty circles) is shown as a function of SEQ alignment accuracy. The curve f...
Template-based modeling (termed also Comparative or Homology Modeling) of a protein structure is one...