The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation-3

Oglycan content. The chondrocyte morphology was analyzed by comparing the chondrocyte size in the three zones of the growth plate. We noticed a reduction of hypertrophic cell size in the case of hypertrophic chondrocytes. (B) E18.5 tibiae treated with LY294002 for 6 days showed the same reduction in hypertrophic zone length and cell size as the E15.5 treated tibiae.<p><b>Copyright information:</b></p><p>Taken from "The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation"</p><p>http://www.biomedcentral.com/1471-213X/8/40</p><p>BMC Developmental Biology 2008;8():40-40.</p><p>Published online 11 Apr 2008</p><p>PMCID:PMC2329617.</p><p>