Colon tumors from four etiologically distinct mouse models of CRC were subjected to microarray gene expression profiling. The gene expression profiles from the different mouse model tumors were compared and contrasted to each other, as well as to those from embryonic mouse colon development and 100 human CRCs.<p><b>Copyright information:</b></p><p>Taken from "Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer"</p><p>http://genomebiology.com/2007/8/7/R131</p><p>Genome Biology 2007;8(7):R131-R131.</p><p>Published online 5 Jul 2007</p><p>PMCID:PMC2323222.</p><p></p
Background: Since the first evidence suggesting existence of stem-like cancer cells, the process of ...
Colon cancers develop after accumulation of multiple genetic and epigenetic alterations in colon epi...
[[abstract]]Although valuable insights into colon cancer biology have been garnered from human colon...
Murine colon tumor adenomas and human CRCs both show adoption and dysregulation of signatures tightl...
When human and murine tumors are compared, they both broadly re-express an embryonic gene expression...
Abstract Background The expression of carcino-embryonic antigen by colorectal cancer is an example o...
Differential expression of transcripts identified by the microarray analyses was examined using qRT-...
<div><p>A connection between colorectal carcinogenesis and inflammation is well known, but the under...
Hierarchical clustering of gene transcripts separates the four models into two groups. The upper pan...
A connection between colorectal carcinogenesis and inflammation is well known, but the underlying mo...
Genes potentially able to distinguish cancer subtypes were identified from Affymetrix HG-U133 plus2 ...
The expression level of each gene in each sample was calculated relative to that in adult colon. Gen...
Colorectal cancer (CRC) is the second most common cancer in Europe and a leading cause of death worl...
The study of experimental colon carcinogenesis in rodents has a long history, dating back almost 80 ...
Current mouse models for colorectal cancer often differ significantly from human colon cancer, being...
Background: Since the first evidence suggesting existence of stem-like cancer cells, the process of ...
Colon cancers develop after accumulation of multiple genetic and epigenetic alterations in colon epi...
[[abstract]]Although valuable insights into colon cancer biology have been garnered from human colon...
Murine colon tumor adenomas and human CRCs both show adoption and dysregulation of signatures tightl...
When human and murine tumors are compared, they both broadly re-express an embryonic gene expression...
Abstract Background The expression of carcino-embryonic antigen by colorectal cancer is an example o...
Differential expression of transcripts identified by the microarray analyses was examined using qRT-...
<div><p>A connection between colorectal carcinogenesis and inflammation is well known, but the under...
Hierarchical clustering of gene transcripts separates the four models into two groups. The upper pan...
A connection between colorectal carcinogenesis and inflammation is well known, but the underlying mo...
Genes potentially able to distinguish cancer subtypes were identified from Affymetrix HG-U133 plus2 ...
The expression level of each gene in each sample was calculated relative to that in adult colon. Gen...
Colorectal cancer (CRC) is the second most common cancer in Europe and a leading cause of death worl...
The study of experimental colon carcinogenesis in rodents has a long history, dating back almost 80 ...
Current mouse models for colorectal cancer often differ significantly from human colon cancer, being...
Background: Since the first evidence suggesting existence of stem-like cancer cells, the process of ...
Colon cancers develop after accumulation of multiple genetic and epigenetic alterations in colon epi...
[[abstract]]Although valuable insights into colon cancer biology have been garnered from human colon...