%, 95%-CI: 65–73%) of the pseudogene transcript levels (lane 3). mRNA levels are normalized to β-actin (yellow bars) and cyclophilin B (blue bars). silencing is associated with a reduction of mRNA expression (84%, p = 0.003, 95%-CI: 76–91%, yellow bar; 82%, p = 0.01, 95%-CI: 72–93%, blue bar, lane 4). A positive control (knock-down of ) is shown (lane 2). Data were obtained from six independent experiments. The relative expression levels before knock-down experiments were set to 100% (lane 1).<p><b>Copyright information:</b></p><p>Taken from "The human ABC transporter pseudogene family: Evidence for transcription and gene-pseudogene interference"</p><p>http://www.biomedcentral.com/1471-2164/9/165</p><p>BMC Genomics 2008;9():165-165.</p><p>P...
BACKGROUND: During the past years, we and others discovered a series of human ATP-binding cassette (...
ATP-binding cassette (ABC) transporters are of major importance for the restricted access of toxins ...
<div><p>Thousands of pseudogenes exist in the human genome and many are transcribed, but their funct...
Lative to those of the housekeeping gene β-actin. Highest expression of both and was observed in adu...
Some 16p13. Arrows indicate the direction of transcription. The structures of the and genes and thei...
BACKGROUND: Pseudogenes are an integral component of the human genome. Little attention, however, ha...
are the chromosomal localizations (colored arrows) of ABC transporter pseudogenes (right-hand side o...
Abstract Background Pseudogenes are an integral component of the human genome. Little attention, how...
are the chromosomal localizations (colored arrows) of ABC transporter pseudogenes (right-hand side o...
ATP binding cassette (ABC) transporters are a family of proteins whose activity is vital to cell det...
ATP-binding cassette (ABC) transporters are integral components of most living cells and constitute ...
The xenobiotic ABC transporters are membrane bound proteins that efflux substrates coupled with ATP ...
The human ATP-binding cassette (ABC) transporters comprise a large family of membrane transport prot...
ATP-binding cassette (ABC) membrane transporters determine the disposition of many drugs, metabolite...
Background During the past years, we and others discovered a series of human ATP-bin...
BACKGROUND: During the past years, we and others discovered a series of human ATP-binding cassette (...
ATP-binding cassette (ABC) transporters are of major importance for the restricted access of toxins ...
<div><p>Thousands of pseudogenes exist in the human genome and many are transcribed, but their funct...
Lative to those of the housekeeping gene β-actin. Highest expression of both and was observed in adu...
Some 16p13. Arrows indicate the direction of transcription. The structures of the and genes and thei...
BACKGROUND: Pseudogenes are an integral component of the human genome. Little attention, however, ha...
are the chromosomal localizations (colored arrows) of ABC transporter pseudogenes (right-hand side o...
Abstract Background Pseudogenes are an integral component of the human genome. Little attention, how...
are the chromosomal localizations (colored arrows) of ABC transporter pseudogenes (right-hand side o...
ATP binding cassette (ABC) transporters are a family of proteins whose activity is vital to cell det...
ATP-binding cassette (ABC) transporters are integral components of most living cells and constitute ...
The xenobiotic ABC transporters are membrane bound proteins that efflux substrates coupled with ATP ...
The human ATP-binding cassette (ABC) transporters comprise a large family of membrane transport prot...
ATP-binding cassette (ABC) membrane transporters determine the disposition of many drugs, metabolite...
Background During the past years, we and others discovered a series of human ATP-bin...
BACKGROUND: During the past years, we and others discovered a series of human ATP-binding cassette (...
ATP-binding cassette (ABC) transporters are of major importance for the restricted access of toxins ...
<div><p>Thousands of pseudogenes exist in the human genome and many are transcribed, but their funct...