The excitation-induced net loss of K and gain of Na in rat soleus and EDL

Experimental conditions as described in the legend to . Following equilibration for 30 min in K.R. buffer, contralateral muscles from the same animal were either allowed to rest or stimulated in air at 60 Hz for 60 s (soleus) or 30 s (EDL). For each pair of contralateral muscles, the excitation-induced loss of K and gain of Na were calculated from the differences in K and Na contents, respectively, and expressed as nmol/pulse/g wet wt (Δ Na and Δ K). Each column represents the mean of observations on 12 muscles with bars denoting SEM, The difference between the excitation-induced Na uptake in soleus and EDL muscles was significant (P = 0.0l4). Likewise, the difference between excitation-induced K release of soleus and EDL muscles was significant (P = 0.011).<p><b>Copyright information:</b></p><p>Taken from "Clearance of Extracellular K during Muscle Contraction—Roles of Membrane Transport and Diffusion"</p><p></p><p>The Journal of General Physiology 2008;131(5):473-481.</p><p>Published online Jan 2008</p><p>PMCID:PMC2346564.</p><p>