(C) ELISA determination of IL-15 protein levels after dissociation of IL-15–IL-15Rα protein complexes with 0.01% SDS and boiling. Lines represent data from WT (▪), (▴), and (▾) BMDCs. All data are representative of at least three separate experiments.<p><b>Copyright information:</b></p><p>Taken from "IL-15Rα chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation"</p><p></p><p>The Journal of Experimental Medicine 2008;205(5):1213-1225.</p><p>Published online 12 May 2008</p><p>PMCID:PMC2373851.</p><p></p
Interleukin-15 (IL15) is one of the most important cytokines currently being considered for cancer t...
International audienceIL-15 and IL-2 are two structurally and functionally related cytokines whose h...
A diverse assortment of infectious pathogens and TLR agonists enhance the expression of Interleukin ...
Sera were collected 24 h after stimulation and IL-15 (B and E), sIL-15Rα (A and D), and IL-15–sIL-15...
BMDCs from various genotypes (indicated along the x axis of graph) were activated with poly I:C and ...
(B) Flow cytometric analysis of DC activation after poly I:C stimulation. Histograms of poly I:C–sti...
International audienceNatural killer (NK) cells are innate immune effectors that mediate rapid respo...
Interleukin (IL)-15 associates with IL-15Rα on the cell surface where it can be cleaved into soluble...
<p>Confluent RK-13 cells in 6-well plates were infected with vMyx-IL15Rα-tdTr or vMyx-tdTr at MOI = ...
ABSTRACT. Interleukin (IL)-15 is a cytokine critical for the homeostasis and the function of NK cell...
<p>A) Western blot demonstrating mIL-15 production in Neuro-2a cells infected by J100 or J100D at a ...
AbstractWe report intriguing aspects of the contribution of IL-15Rα to IL-15 functions. Consistent w...
<p>CD34<sup>+</sup> PB- and BM-HP were committed to the NK cell lineage, culturing in STEMα Α medium...
Natural killer (NK) cells are innate immune effectors that mediate rapid responses to viral antigens...
<p>Activated NK cells upregulate the expression of the high affinity α subunit of IL-15R. <b>A</b>. ...
Interleukin-15 (IL15) is one of the most important cytokines currently being considered for cancer t...
International audienceIL-15 and IL-2 are two structurally and functionally related cytokines whose h...
A diverse assortment of infectious pathogens and TLR agonists enhance the expression of Interleukin ...
Sera were collected 24 h after stimulation and IL-15 (B and E), sIL-15Rα (A and D), and IL-15–sIL-15...
BMDCs from various genotypes (indicated along the x axis of graph) were activated with poly I:C and ...
(B) Flow cytometric analysis of DC activation after poly I:C stimulation. Histograms of poly I:C–sti...
International audienceNatural killer (NK) cells are innate immune effectors that mediate rapid respo...
Interleukin (IL)-15 associates with IL-15Rα on the cell surface where it can be cleaved into soluble...
<p>Confluent RK-13 cells in 6-well plates were infected with vMyx-IL15Rα-tdTr or vMyx-tdTr at MOI = ...
ABSTRACT. Interleukin (IL)-15 is a cytokine critical for the homeostasis and the function of NK cell...
<p>A) Western blot demonstrating mIL-15 production in Neuro-2a cells infected by J100 or J100D at a ...
AbstractWe report intriguing aspects of the contribution of IL-15Rα to IL-15 functions. Consistent w...
<p>CD34<sup>+</sup> PB- and BM-HP were committed to the NK cell lineage, culturing in STEMα Α medium...
Natural killer (NK) cells are innate immune effectors that mediate rapid responses to viral antigens...
<p>Activated NK cells upregulate the expression of the high affinity α subunit of IL-15R. <b>A</b>. ...
Interleukin-15 (IL15) is one of the most important cytokines currently being considered for cancer t...
International audienceIL-15 and IL-2 are two structurally and functionally related cytokines whose h...
A diverse assortment of infectious pathogens and TLR agonists enhance the expression of Interleukin ...