Alu content in flanking regions of recent expression profile modification and conserved housekeeping or tissue-specific genes

Each data subset of human housekeeping genes (expressed in 30 or 31 tissues of 31 in total) and tissue-specific genes (expressed in 1 or 2 tissues from 31 in total) was divided into two groups according to whether their mouse ortholog was a housekeeping or tissue-specific gene (if expressed in 30 to 31 or 1 to 2 tissues, respectively). The left panel shows human housekeeping genes for which the mouse counterparts are also housekeeping (orange columns) or tissue-specific instead (red columns). The right panel shows Alu content in tissue-specific human genes for which the mouse counterparts are also tissue specific or housekeeping instead. Stars represent significant differences in between the two groups with a P < 0.05 (*) and 0.01 (**) on a Students T-test.<p><b>Copyright information:</b></p><p>Taken from "Do Alu repeats drive the evolution of the primate transcriptome?"</p><p>http://genomebiology.com/2008/9/2/R25</p><p>Genome Biology 2008;9(2):R25-R25.</p><p>Published online 1 Feb 2008</p><p>PMCID:PMC2374697.</p><p>