Immunohistochemical staining of breast carcinoma with polyclonal antibody against derlin-1

Positive derlin-1 labeling in a breast cancer section. Note that the immunoreactivity was limited to the cytoplasm of the neoplastic cells. Negative derlin-1 labeling in the section from the same breast cancer tissue block when derlin-1 antibody was pre-incubated with the corresponding peptide antigen. The absence of signal was scored as '0'. Low-intensity signal was scored as '1'. Moderate-intensity signal was scored as '2'. High-intensity signal was scored as '3'. Bars, 50 μm.<p><b>Copyright information:</b></p><p>Taken from "Derlin-1 is overexpressed in human breast carcinoma and protects cancer cells from endoplasmic reticulum stress-induced apoptosis"</p><p>http://breast-cancer-research.com/content/10/1/R7</p><p>Breast Cancer Research : BCR 2008;10(1):R7-R7.</p><p>Published online 20 Jan 2008</p><p>PMCID:PMC2374959.</p><p>