Tibody (red). A mutant clone at the DV boundary (indicated by the white box) is shown at higher magnification in the inset in (D). * mutant clones are indicated by the absence of nuclear GFP (C). Some * cells (indicated by arrows) at the clone boundary are Cut-positive (see text for explanation). Scale bar, 50 μm.<p><b>Copyright information:</b></p><p>Taken from "The clathrin-binding motif and the J-domain of are essential for facilitating Notch ligand endocytosis"</p><p>http://www.biomedcentral.com/1471-213X/8/50</p><p>BMC Developmental Biology 2008;8():50-50.</p><p>Published online 8 May 2008</p><p>PMCID:PMC2391152.</p><p></p
The clathrin heavy chain N-terminal domain interacts with endocytic adapter proteins via clathrin bi...
Clathrin is a coat protein that mediates membrane traffic by capturing and transporting cargo betwee...
Expression of Notch signaling targets Wg (A) and Cut (B) are abolished in me31Bk06607 homozygous mut...
Th mAB323 anti-E(spl) antibody (red). , and * mutant cells are indicated by the absence of nuclear G...
(D-F) Notch receptor (red in merged panel). * mutant cells are indicated by the absence of nuclear G...
G-J, and basal: D-F and K-N). For panels A-F, EGFP-tagged Clc, expressed in all cells, is shown in g...
Western blot of extracts from flies expressing dAux-mRFP (lane 1), dAux-mRFP (lane 2), dAux-mRFP (la...
Background Ligand endocytosis plays a critical role in regulating the activity of the Notch pathway....
Notch signaling is a highly conserved pathway that plays numerous roles during cell fate decisions a...
SummaryClathrin-mediated endocytosis (CME) regulates many cell physiological processes such as the i...
Clathrin-mediated endocytosis (CME) regulates many cell physiological processes such as the internal...
AbstractClathrin is a trimeric protein involved in receptor-mediated-endocytosis, but can function a...
AbstractThe Notch signalling pathway is widely utilised during embryogenesis in situations where cel...
Using real-time TIRF microscopy imaging, we identify sites of clathrin and dynamin-independent CLIC/...
<p>A) Complexes of K<sub>V</sub>10.1-BBS with BTX-Alexa594 (red) colocalize with clathrin-GFP (green...
The clathrin heavy chain N-terminal domain interacts with endocytic adapter proteins via clathrin bi...
Clathrin is a coat protein that mediates membrane traffic by capturing and transporting cargo betwee...
Expression of Notch signaling targets Wg (A) and Cut (B) are abolished in me31Bk06607 homozygous mut...
Th mAB323 anti-E(spl) antibody (red). , and * mutant cells are indicated by the absence of nuclear G...
(D-F) Notch receptor (red in merged panel). * mutant cells are indicated by the absence of nuclear G...
G-J, and basal: D-F and K-N). For panels A-F, EGFP-tagged Clc, expressed in all cells, is shown in g...
Western blot of extracts from flies expressing dAux-mRFP (lane 1), dAux-mRFP (lane 2), dAux-mRFP (la...
Background Ligand endocytosis plays a critical role in regulating the activity of the Notch pathway....
Notch signaling is a highly conserved pathway that plays numerous roles during cell fate decisions a...
SummaryClathrin-mediated endocytosis (CME) regulates many cell physiological processes such as the i...
Clathrin-mediated endocytosis (CME) regulates many cell physiological processes such as the internal...
AbstractClathrin is a trimeric protein involved in receptor-mediated-endocytosis, but can function a...
AbstractThe Notch signalling pathway is widely utilised during embryogenesis in situations where cel...
Using real-time TIRF microscopy imaging, we identify sites of clathrin and dynamin-independent CLIC/...
<p>A) Complexes of K<sub>V</sub>10.1-BBS with BTX-Alexa594 (red) colocalize with clathrin-GFP (green...
The clathrin heavy chain N-terminal domain interacts with endocytic adapter proteins via clathrin bi...
Clathrin is a coat protein that mediates membrane traffic by capturing and transporting cargo betwee...
Expression of Notch signaling targets Wg (A) and Cut (B) are abolished in me31Bk06607 homozygous mut...