Quantitative real time-PCR analysis of (A), (B) and mRNA (C) for COX-2and COX-2mice 24 h after icv injection of LPS or vehicle

(D) Quantification of phosphorylated STAT3 (Tyr 705) protein levels, relative to the total STAT3 in the brain nuclear fraction. (E) Representative immunoblot of P-STAT3 expression in COX-2and COX-2mice 24 h after icv injection of LPS or vehicle. Data are presented as mean ± SEM (= 4-6). *< 0.05, **< 0.01, ***< 0.001 compared to the corresponding vehicle-injected mice; < 0.01 compared to the LPS-injected COX-2mice.<p><b>Copyright information:</b></p><p>Taken from "Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2"</p><p>http://www.jneuroinflammation.com/content/5/1/17</p><p>Journal of Neuroinflammation 2008;5():17-17.</p><p>Published online 19 May 2008</p><p>PMCID:PMC2409311.</p><p>