Is functionally conserved and required for oogenesis and larval growth-1

Ults are sterile and thinner than control heterozygotes. Oocytes (C) and embryos (F) are visible in a control heterozygote but homozygotes have no (D) or only a few oocytes (E). G. Structures resembling embryos are occasionally seen in the uterus of homozygotes. Asterisk, spermatheca; e, embryo or embryo-like structure; g, gonad; i, intestine; o, oocyte; u, uterus. H. The average number of oocytes in homozygotes is reduced. Oocytes were identified either by Nomarski optics or by DAPI staining. n, number of individual gonad arms examined; ND, not determined. I. Spermatocytes (arrow) are still present in a homozygote. I'. DAPI staining. Asterisk marks the more differentiated spermatids. J. Intestinal epithelial cell nuclei can be visualized by DAPI staining in a control N2 L4 worm. K. In homozygotes an expanded intestinal lumen filled with bacteria can be seen. L. The pharynx is often twisted, possibly by pressure from the enlarged intestine.<p><b>Copyright information:</b></p><p>Taken from "is functionally conserved and required for oogenesis and larval growth"</p><p>http://www.biomedcentral.com/1471-213X/8/51</p><p>BMC Developmental Biology 2008;8():51-51.</p><p>Published online 9 May 2008</p><p>PMCID:PMC2409312.</p><p>