Multilineage hematopoietic recovery with concomitant antitumor effects using low dose Interleukin-12 in myelosuppressed tumor-bearing mice-10

for neutrophils (A and B), lymphocytes (C and D) and monocytes (E and F). Pre-radiation blood values reflect an average of all animals in both groups (70 mice) before radiation and tumor inoculation. The normal threshold values for neutrophil, lymphocyte and monocyte counts in C57BL/6 mice are indicated. Following the initial dose of vehicle or cytokine, 4 subsequent doses were given every 3–4 days following radiation. IL-12 treated mice received a total dose (5 single doses) of 220 ng, whereas G-CSF treated mice received a total dose (5 single doses) of 5 μg.<p><b>Copyright information:</b></p><p>Taken from "Multilineage hematopoietic recovery with concomitant antitumor effects using low dose Interleukin-12 in myelosuppressed tumor-bearing mice"</p><p>http://www.translational-medicine.com/content/6/1/26</p><p>Journal of Translational Medicine 2008;6():26-26.</p><p>Published online 19 May 2008</p><p>PMCID:PMC2424034.</p><p>