reflect an average of all animals in both groups (70 mice) before radiation and tumor inoculation. The normal threshold value for murine red blood cell counts is indicated. Following the initial dose of vehicle or cytokine, 4 subsequent doses were given every 3–4 days following radiation. IL-12 treated mice received a total dose (5 single doses) of 220 ng, whereas G-CSF treated mice received a total dose (5 single doses) of 5 μg.<p><b>Copyright information:</b></p><p>Taken from "Multilineage hematopoietic recovery with concomitant antitumor effects using low dose Interleukin-12 in myelosuppressed tumor-bearing mice"</p><p>http://www.translational-medicine.com/content/6/1/26</p><p>Journal of Translational Medicine 2008;6():26-26.</p><p>Publi...
<p>a) Flow cytometry of fresh whole peripheral blood from i) naïve mice or mice bearing 4T1 tumors i...
<p>HCa-1 and MIH-2 cells were injected intramuscularly into the right thighs of the mice, and tumors...
Radiation therapy (RT) recruits myeloid cells, leading to an immunosuppressive microenvironment that...
S reflect an average of all animals in both groups (70 mice) before radiation and tumor inoculation....
Ect an average of all animals in both groups (70 mice) before radiation and tumor inoculation. The n...
for neutrophils (A and B), lymphocytes (C and D) and monocytes (E and F). Pre-radiation blood values...
) for neutrophils (A and B), lymphocytes (C and D) and monocytes (E and F). Pre-radiation blood valu...
Lues reflect an average of all animals in both groups (80 mice) before cyclophosphamide and tumor in...
Odel (B). Mice in both tumor models were given 625 rad at day 1. Mice in the EL4 lymphoma tumor mode...
) for neutrophils (A and B), lymphocytes (C and D) and monocytes (E and F). Pre-chemotherapy blood v...
left), G-CSF (top, middle) and IL-12 pre-post (top, right) are shown. For the Lewis lung cancer mode...
was 5 weeks from the first round of cyclophosphamide treatment and 7 weeks after tumor inoculation. ...
Odel (B). IL-12 treatment significantly reduces tumor growth following cyclophosphamide treatment in...
<p><b>Applied myelosuppressive regimen models: (A) chemo/radiotherapy model—whole-body irradiation i...
<p>a) i) Flow cytometry of fresh whole peripheral blood from naïve and 4T1 tumor-bearing BALB/c mice...
<p>a) Flow cytometry of fresh whole peripheral blood from i) naïve mice or mice bearing 4T1 tumors i...
<p>HCa-1 and MIH-2 cells were injected intramuscularly into the right thighs of the mice, and tumors...
Radiation therapy (RT) recruits myeloid cells, leading to an immunosuppressive microenvironment that...
S reflect an average of all animals in both groups (70 mice) before radiation and tumor inoculation....
Ect an average of all animals in both groups (70 mice) before radiation and tumor inoculation. The n...
for neutrophils (A and B), lymphocytes (C and D) and monocytes (E and F). Pre-radiation blood values...
) for neutrophils (A and B), lymphocytes (C and D) and monocytes (E and F). Pre-radiation blood valu...
Lues reflect an average of all animals in both groups (80 mice) before cyclophosphamide and tumor in...
Odel (B). Mice in both tumor models were given 625 rad at day 1. Mice in the EL4 lymphoma tumor mode...
) for neutrophils (A and B), lymphocytes (C and D) and monocytes (E and F). Pre-chemotherapy blood v...
left), G-CSF (top, middle) and IL-12 pre-post (top, right) are shown. For the Lewis lung cancer mode...
was 5 weeks from the first round of cyclophosphamide treatment and 7 weeks after tumor inoculation. ...
Odel (B). IL-12 treatment significantly reduces tumor growth following cyclophosphamide treatment in...
<p><b>Applied myelosuppressive regimen models: (A) chemo/radiotherapy model—whole-body irradiation i...
<p>a) i) Flow cytometry of fresh whole peripheral blood from naïve and 4T1 tumor-bearing BALB/c mice...
<p>a) Flow cytometry of fresh whole peripheral blood from i) naïve mice or mice bearing 4T1 tumors i...
<p>HCa-1 and MIH-2 cells were injected intramuscularly into the right thighs of the mice, and tumors...
Radiation therapy (RT) recruits myeloid cells, leading to an immunosuppressive microenvironment that...