Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition-1

reversible and observed in 35.7% of the lamina II neurons. Histograms on the right show the mean increase (± SEM) in frequency (with respect to control) of sEPSCs and mEPSCs. : Elevation in the frequency of occurrence of GABAA-R sIPSCs was observed in all lamina II neurons recorded (n = 6 out of 6; raw traces and histogram on the left). However, TGOT never changed the frequency of miniature GABAA-R events (right histogram). Asterisks indicate statistical significance using Student's t-test, p < 0.05.<p><b>Copyright information:</b></p><p>Taken from "Oxytocin-induced antinociception in the spinal cord is mediated by a subpopulation of glutamatergic neurons in lamina I-II which amplify GABAergic inhibition"</p><p>http://www.molecularpain.com/content/4/1/19</p><p>Molecular Pain 2008;4():19-19.</p><p>Published online 29 May 2008</p><p>PMCID:PMC2430948.</p><p>