- and -related genes in the annelid : insights into the evolution of neural basic-Helix-Loop-Helix genes-0

Are ImageJ projections and are ventral views (anterior up). The blue dotted lines indicate the position of the prototroch (a ring of ciliated cells involved in the locomotion of the larva) and therefore the separation between the prospective head (up) and trunk (down) regions. The position of the mouth region is indicated either by dotted red lines or a red asterisk, depending on the stage. The formation of the larval neurons is shown in A to E. A few neurons with stereotyped positions differentiate between 24 h to 48 h as seen by the expression of and (A-C). A single pair of neurons, located close to the mouth region, is serotonergic as seen by the expression of (D), a few other neurons are cholinergic (as seen by the expression of ; E), and the other ones are of unknown identity. F to L depict the formation of the juvenile worm nervous system. See the main text for details. Arrows in J point to peripheral neurons associated with the parapodes. M to O are schematic drawings of the organization of the nervous system of 24 hpf, 48 hpf, and 72 hpf larvae. The neuroectodermal cells are indicated in yellow, the cells expressing in red, and the -expressing neurons in blue.<p><b>Copyright information:</b></p><p>Taken from "- and -related genes in the annelid : insights into the evolution of neural basic-Helix-Loop-Helix genes"</p><p>http://www.biomedcentral.com/1471-2148/8/170</p><p>BMC Evolutionary Biology 2008;8():170-170.</p><p>Published online 9 Jun 2008</p><p>PMCID:PMC2435551.</p><p>