The protein C (PC) categories were normal (> 80%), deficient (41% to 80%), and severely deficient (< 40%). The number in each column is the total number of patients in each category. Patients were included if they had a baseline PC measure. Day 4 PC was classified as end of infusion. If day 4 measurement was not available, last observation carried forward values were used for classification. These data were reported by Vangerow and coworkers [42]. ENHANCE, Extended Evaluation of Recombinant Activated Protein C; PROWESS, Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.<p><b>Copyright information:</b></p><p>Taken from "Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment wi...
C concentrates in patients without congenital deficit: a systematic review of the literature Endogen...
AbstractIn 2001, the PROWESS (Recombinant Human Activated Protein C Worldwide Evaluation in Severe S...
Endogenous protein C levels are frequently decreased in septic patients, probably due to increased c...
Protein C (PC) de ciency is prevalent in severe sepsis, studies showing that more than 80% of patie...
PROWESS, Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.<p><b>Copyright...
International audienceINTRODUCTION: Serial alterations in protein C levels appear to correlate with ...
AIM The aim of this study was the assessment of the efficacy of recombinant human activated protein ...
Protein C plays an important role in the coagulopathy associated with sepsis and probably also in th...
Identification of good surrogate end-points can greatly facilitate the design of clinical trials. Us...
Meeting abstractIntroduction Activated protein C (APC) deC ciency is prevalent in severe sepsis and ...
Objective: To assess the effects of drotrecogin alfa (activated) therapy, a recombinant human activa...
OBJECTIVE: Evidence regarding the efficacy and safety of human recombinant activated protein C in se...
Objective: To describe the efficacy and safety of protein C (PC) concentrate to restore physiologica...
Background: Drotrecogin alfa (activated), or recombinant human activated protein C, has antithrombot...
Introduction: Activated Protein C [APC] improves outcome in immunocompetent patients with severe sep...
C concentrates in patients without congenital deficit: a systematic review of the literature Endogen...
AbstractIn 2001, the PROWESS (Recombinant Human Activated Protein C Worldwide Evaluation in Severe S...
Endogenous protein C levels are frequently decreased in septic patients, probably due to increased c...
Protein C (PC) de ciency is prevalent in severe sepsis, studies showing that more than 80% of patie...
PROWESS, Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.<p><b>Copyright...
International audienceINTRODUCTION: Serial alterations in protein C levels appear to correlate with ...
AIM The aim of this study was the assessment of the efficacy of recombinant human activated protein ...
Protein C plays an important role in the coagulopathy associated with sepsis and probably also in th...
Identification of good surrogate end-points can greatly facilitate the design of clinical trials. Us...
Meeting abstractIntroduction Activated protein C (APC) deC ciency is prevalent in severe sepsis and ...
Objective: To assess the effects of drotrecogin alfa (activated) therapy, a recombinant human activa...
OBJECTIVE: Evidence regarding the efficacy and safety of human recombinant activated protein C in se...
Objective: To describe the efficacy and safety of protein C (PC) concentrate to restore physiologica...
Background: Drotrecogin alfa (activated), or recombinant human activated protein C, has antithrombot...
Introduction: Activated Protein C [APC] improves outcome in immunocompetent patients with severe sep...
C concentrates in patients without congenital deficit: a systematic review of the literature Endogen...
AbstractIn 2001, the PROWESS (Recombinant Human Activated Protein C Worldwide Evaluation in Severe S...
Endogenous protein C levels are frequently decreased in septic patients, probably due to increased c...