Of irradiated and bone marrow reconstituted (XRT, n = 10/group) (A and B) or naïve (no XRT, n = 5/group) mice (C). D. Summary of the effect of irradiation and bone marrow reconstitution on the growth of Wnt-1 tumors implanted subcutaneously (S.C.) or into MFP. Data are presented as tumor volume at day 60 for s.c. and at day 50 for MFP after implantation. Mice were treated with 1.5 mg/kg of Rapamycin for 30 days in s.c. groups (A and D) or 20 days in MFP groups (B, C and D) starting the day after tumor implantation (arrows). Tumor size was calculated as described in Methods.<p><b>Copyright information:</b></p><p>Taken from "Rapamycin delays growth of Wnt-1 tumors in spite of suppression of host immunity"</p><p>http://www.biomedcentral.com/14...
<p>(A) Tumor sizes of the SCC tumors in the mice leg treated with vehicle (control, •), 5 mg/kg bw/d...
<p>(A–D) Timm staining shows mossy fiber sprouting from control mice (Ctrl+Veh, A), and vehicle-trea...
Suppression of tumor metastasis is a key strategy for successful cancer interventions. Pre-vious stu...
Of irradiated and bone marrow reconstituted (XRT, n = 10/group) (A and B) or naïve (no XRT, n = 5/gr...
T-1 tumor cells. C and D. Proliferation of normal CD3/28 activated splenocytes (pooled from 5 mice) ...
With Rapamycin in vivo for 7 and 20 days (n = 5/group). B and C. Spontaneous apoptosis in splenocyte...
F Wnt-1 tumor cells were incubated for 72 hours with or without 1 μM of Rapamycin. Wnt-1 cells were ...
<p>Growth kinetics of SCC tumors implanted in mice leg, treated with vehicle (control, •), X-irradia...
Cubated with or without 1 μM Rapamycin for 24 hours, labeled with DiOCand stained with annexinV-APC....
<p>Anatomy, pO<sub>2</sub>, and blood volume images of SCC tumor in mice leg treated with vehicle (A...
<p>(A) The timeline for the pre-immunity models. Animals were primed with an intraperitoneal dose of...
<p>Following necropsy, colonic tumor tissue with adjacent colon epithelial tissue was formalin-fixed...
<p>Naïve WT and MyD88ΔT mice were CD4<sup>+</sup> T cell depleted and vaccinated with strain #55. Ra...
<p>(A-F) Volume of the xenograft tumors was measured in mice injected with doxorubicin (0.75 mg/kg),...
<p><b>(A)</b> Cells were plated in culture dishes and were irradiated after 24 hours. Each data poin...
<p>(A) Tumor sizes of the SCC tumors in the mice leg treated with vehicle (control, •), 5 mg/kg bw/d...
<p>(A–D) Timm staining shows mossy fiber sprouting from control mice (Ctrl+Veh, A), and vehicle-trea...
Suppression of tumor metastasis is a key strategy for successful cancer interventions. Pre-vious stu...
Of irradiated and bone marrow reconstituted (XRT, n = 10/group) (A and B) or naïve (no XRT, n = 5/gr...
T-1 tumor cells. C and D. Proliferation of normal CD3/28 activated splenocytes (pooled from 5 mice) ...
With Rapamycin in vivo for 7 and 20 days (n = 5/group). B and C. Spontaneous apoptosis in splenocyte...
F Wnt-1 tumor cells were incubated for 72 hours with or without 1 μM of Rapamycin. Wnt-1 cells were ...
<p>Growth kinetics of SCC tumors implanted in mice leg, treated with vehicle (control, •), X-irradia...
Cubated with or without 1 μM Rapamycin for 24 hours, labeled with DiOCand stained with annexinV-APC....
<p>Anatomy, pO<sub>2</sub>, and blood volume images of SCC tumor in mice leg treated with vehicle (A...
<p>(A) The timeline for the pre-immunity models. Animals were primed with an intraperitoneal dose of...
<p>Following necropsy, colonic tumor tissue with adjacent colon epithelial tissue was formalin-fixed...
<p>Naïve WT and MyD88ΔT mice were CD4<sup>+</sup> T cell depleted and vaccinated with strain #55. Ra...
<p>(A-F) Volume of the xenograft tumors was measured in mice injected with doxorubicin (0.75 mg/kg),...
<p><b>(A)</b> Cells were plated in culture dishes and were irradiated after 24 hours. Each data poin...
<p>(A) Tumor sizes of the SCC tumors in the mice leg treated with vehicle (control, •), 5 mg/kg bw/d...
<p>(A–D) Timm staining shows mossy fiber sprouting from control mice (Ctrl+Veh, A), and vehicle-trea...
Suppression of tumor metastasis is a key strategy for successful cancer interventions. Pre-vious stu...