Large gene overlaps in prokaryotic genomes: result of functional constraints or mispredictions?-2

Ransferase) genes among Enterobacteria. A) Multiple alignment of the C-terminal of the DNA polymerase psi subunit and the N-terminal of the alanine acetyltransferase protein among Enterobacteria species. The grey boxes indicate the fragments that are encoded in the overlapping region between and genes. The alignments of Escherichia & Shigella, Salmonella and Yersinia are marked. B) Arrangement of overlapping regions and amino acid conservation within the overlap among K12, Ty2 and CO92. The nucleotide consensus shows an asterisk for the conserved nucleotides and a dot for the not conserved. Although we chose one species of each group marked in part A (Escherichia & Shigella, Salmonella and Yersinia) we can observe the high similarity at the level of sample nucleotide sequences too.<p><b>Copyright information:</b></p><p>Taken from "Large gene overlaps in prokaryotic genomes: result of functional constraints or mispredictions?"</p><p>http://www.biomedcentral.com/1471-2164/9/335</p><p>BMC Genomics 2008;9():335-335.</p><p>Published online 15 Jul 2008</p><p>PMCID:PMC2478687.</p><p>