Peptide-specific CD8 T cell responses against the HIV-1 Gag antigen in mice immunized with Gag or with the combination Gag and Tat

After 3 immunizations, fresh splenocytes were pooled and purified, then CD8+ T cells were tested by IFNγ Elispot assay after stimulation with the indicated 15 mers (panel A), or with the indicated 8–10 mers derived from the above 15 mers (panel B). Results from mice immunized with Gag (empty bars) and from mice immunized with Gag and Tat (filled bars) are expressed as SFU ± SD/10cells. The mean +/- SD of three independent experiments is shown.<p><b>Copyright information:</b></p><p>Taken from "Identification of new HIV-1 Gag-specific cytotoxic T lymphocyte responses in BALB/c mice"</p><p>http://www.virologyj.com/content/5/1/81</p><p>Virology Journal 2008;5():81-81.</p><p>Published online 14 Jul 2008</p><p>PMCID:PMC2481256.</p><p>