ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages-3

or without pre-treatment with wortmannin (100 nM/1 hour) or oATP (0.3 mM/2 hours). The kinetics of BCG viability was determined by H-uridine incorporation, monitored at various times post treatment. The figure illustrates the pattern of results obtained from three separate experiments performed in triplicate. The symbols indicate mean values, and vertical bars indicate the standard error. The significance of the various treatment relative to the untreated control are illustrated by: ** = P < 0.005 * = P < 0.05. The results from one H-uridine uptake assay are tabulated as mean counts per minute (CPM) data +/- SEM at each time point examined.<p><b>Copyright information:</b></p><p>Taken from "ATP-induced autophagy is associated with rapid killing of intracellular mycobacteria within human monocytes/macrophages"</p><p>http://www.biomedcentral.com/1471-2172/9/35</p><p>BMC Immunology 2008;9():35-35.</p><p>Published online 15 Jul 2008</p><p>PMCID:PMC2483257.</p><p>