(A) Mean values for the time constants of the dequenching component of fluorescence measured from TMRM attached to either M394C or A397C and the time constants of the associated ionic current activation, measured between +10 and +60 mV. (B) Relative amplitude of the dequenching component of fluorescence, normalized to the total fluorescence deflection on depolarization, measured from TMRM attached at either M394C or A397C.<p><b>Copyright information:</b></p><p>Taken from "Voltage Clamp Fluorimetry Reveals a Novel Outer Pore Instability in a Mammalian Voltage-gated Potassium Channel"</p><p></p><p>The Journal of General Physiology 2008;132(2):209-222.</p><p>Published online Jan 2008</p><p>PMCID:PMC2483330.</p><p></p
The voltage-gated potassium channels of the Kv1 (Shaker-type) family are proteins found in many cell...
This thesis aims to study the activation and deactivation mechanism of voltage-gated K+ channels (Kv...
(A) Representative current traces from an oocyte expressing Kv1.2-R294H-A351H-D352G-E353S channels r...
(A) Ionic currents and fluorescence signals recorded from TMRM attached at A397C during a 100-ms tes...
(A and B) Ionic current and fluorescence signals recorded during the voltage protocol shown. The tim...
(A and B) Ionic current and fluorescence signals recorded from TMRM-labeled Kv1.5 A397C channels dur...
Voltage-gated potassium (Kv) channels are essential membrane proteins in modulating membrane excitab...
Kv channels are voltage-dependent potassium pores that shape the action potential duration and are c...
Kv channels are voltage-dependent potassium pores that shape the action potential duration and are c...
Kv channels are voltage-dependent potassium pores that shape the action potential duration and are c...
AbstractWe examined voltage-dependent conformational changes in three specific regions of the Shaker...
<p>(<b>A1-A4</b>) Representative fluorescence signals for DIII-VCF, E1784K-DIII-VCF, DIV-VCF, and E1...
Voltage clamp fluorometry (VCF) was first developed in the mid 1990s by Isacoff and his colleagues. ...
Voltage clamp fluorometry (VCF) was first developed in the mid 1990s by Isacoff and his colleagues. ...
The voltage-gated potassium channels of the Kv1 (Shaker-type) family are proteins found in many cell...
The voltage-gated potassium channels of the Kv1 (Shaker-type) family are proteins found in many cell...
This thesis aims to study the activation and deactivation mechanism of voltage-gated K+ channels (Kv...
(A) Representative current traces from an oocyte expressing Kv1.2-R294H-A351H-D352G-E353S channels r...
(A) Ionic currents and fluorescence signals recorded from TMRM attached at A397C during a 100-ms tes...
(A and B) Ionic current and fluorescence signals recorded during the voltage protocol shown. The tim...
(A and B) Ionic current and fluorescence signals recorded from TMRM-labeled Kv1.5 A397C channels dur...
Voltage-gated potassium (Kv) channels are essential membrane proteins in modulating membrane excitab...
Kv channels are voltage-dependent potassium pores that shape the action potential duration and are c...
Kv channels are voltage-dependent potassium pores that shape the action potential duration and are c...
Kv channels are voltage-dependent potassium pores that shape the action potential duration and are c...
AbstractWe examined voltage-dependent conformational changes in three specific regions of the Shaker...
<p>(<b>A1-A4</b>) Representative fluorescence signals for DIII-VCF, E1784K-DIII-VCF, DIV-VCF, and E1...
Voltage clamp fluorometry (VCF) was first developed in the mid 1990s by Isacoff and his colleagues. ...
Voltage clamp fluorometry (VCF) was first developed in the mid 1990s by Isacoff and his colleagues. ...
The voltage-gated potassium channels of the Kv1 (Shaker-type) family are proteins found in many cell...
The voltage-gated potassium channels of the Kv1 (Shaker-type) family are proteins found in many cell...
This thesis aims to study the activation and deactivation mechanism of voltage-gated K+ channels (Kv...
(A) Representative current traces from an oocyte expressing Kv1.2-R294H-A351H-D352G-E353S channels r...