Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-4

Subsequently, mice were euthanized and lungs were examined histopathologically as described in Materials and Methods and the degree of lung fibrosis per mouse lung was calculated according to the grading system described by Ashcroft et al. []. Representative photomicrographs of Elastica van Gieson-stained lung tissue sections collected from wild-type mice and cath K tg mice at day 28 post-bleomycin treatment. The data are shown as mean ± SD of at least n = 6 mice per group and time point. * indicates significant increase (< 0.05) compared to cathepsin K tg mice.<p><b>Copyright information:</b></p><p>Taken from "Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis"</p><p>http://respiratory-research.com/content/9/1/54</p><p>Respiratory Research 2008;9(1):54-54.</p><p>Published online 18 Jul 2008</p><p>PMCID:PMC2490691.</p><p>