The wells and gp120-specific IgG or IgM were detected with alkaline phosphatase-conjugated rabbit Abs specific for the respective mouse IgG or IgM.<p><b>Copyright information:</b></p><p>Taken from "Antibodies to the CD4-binding site of HIV-1 gp120 suppress gp120-specific CD4 T cell response while enhancing antibody response"</p><p>http://www.infectagentscancer.com/content/3/1/11</p><p>Infectious Agents and Cancer 2008;3():11-11.</p><p>Published online 18 Jul 2008</p><p>PMCID:PMC2503958.</p><p></p
<p>BALB/c mice were immunized once with DNA encoding the indicated vaccine constructs. DNA (25 µg DN...
The rabbit is a commonly used animal model in studying antibody responses in HIV/AIDS vaccine develo...
<p><b>(A)</b> Serum of immunized mice from the memory phase were analyzed for total IgG response usi...
MAb (1418), along with Ribi adjuvant. Each animal received 3 μg of gp120 and 10 μg of mAb. Control m...
Bs mAb 654 or anti-C5 mAb 450 (10 μg/ml each). B) Proliferation of clone T1 was tested in response t...
Nt. (B) Mice were immunized five times i.p. with the same envelope antigens and Ribi adjuvant. Splen...
The in vitro suppressive effect of gp120 and gp120/anti-gp120 antibody is well known but not yet pro...
Tests show the monoclonal anti-CD4 antibody (mAb) MT310 recognizes the gp120-binding site on CD4 as ...
<p>ELISA wells were coated with gp120<sub>MN</sub> or with MCPs listed in the Table, and antibody ti...
AbstractThe binding of antibodies to the CD4-binding site (CD4bs) of the HIV-1 envelope glycoprotein...
The anti-human immunodeficiency virus type 1 (HIV-1) immune responseis erroneously focused on highly...
Conserved regions on the HIV-1 envelope spike are important for vaccine design due to their vulnerab...
Since its discovery in 1981, HIV-1 has infected almost 78 million people, and ~39 million people hav...
<p>(<b>a</b>) Representative FACS data from rCD4s purified from healthy controls (H1, H2) or chronic...
AbstractDifferent isolates of HIV-1 are known to vary in antibody binding and sensitivity to neutral...
<p>BALB/c mice were immunized once with DNA encoding the indicated vaccine constructs. DNA (25 µg DN...
The rabbit is a commonly used animal model in studying antibody responses in HIV/AIDS vaccine develo...
<p><b>(A)</b> Serum of immunized mice from the memory phase were analyzed for total IgG response usi...
MAb (1418), along with Ribi adjuvant. Each animal received 3 μg of gp120 and 10 μg of mAb. Control m...
Bs mAb 654 or anti-C5 mAb 450 (10 μg/ml each). B) Proliferation of clone T1 was tested in response t...
Nt. (B) Mice were immunized five times i.p. with the same envelope antigens and Ribi adjuvant. Splen...
The in vitro suppressive effect of gp120 and gp120/anti-gp120 antibody is well known but not yet pro...
Tests show the monoclonal anti-CD4 antibody (mAb) MT310 recognizes the gp120-binding site on CD4 as ...
<p>ELISA wells were coated with gp120<sub>MN</sub> or with MCPs listed in the Table, and antibody ti...
AbstractThe binding of antibodies to the CD4-binding site (CD4bs) of the HIV-1 envelope glycoprotein...
The anti-human immunodeficiency virus type 1 (HIV-1) immune responseis erroneously focused on highly...
Conserved regions on the HIV-1 envelope spike are important for vaccine design due to their vulnerab...
Since its discovery in 1981, HIV-1 has infected almost 78 million people, and ~39 million people hav...
<p>(<b>a</b>) Representative FACS data from rCD4s purified from healthy controls (H1, H2) or chronic...
AbstractDifferent isolates of HIV-1 are known to vary in antibody binding and sensitivity to neutral...
<p>BALB/c mice were immunized once with DNA encoding the indicated vaccine constructs. DNA (25 µg DN...
The rabbit is a commonly used animal model in studying antibody responses in HIV/AIDS vaccine develo...
<p><b>(A)</b> Serum of immunized mice from the memory phase were analyzed for total IgG response usi...