Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice-17

Were processed for immunohistochemistry to detect activated microglia using an anti-F4/80 specific monoclonal antibody () and astrocytes using an anti-GFAP specific monoclonal antibody (). Primary motor cortex was examined for patterns of immunopositivity and photomicrographs were obtained at 10×. The insets in panels and represent 40× digitally magnified images of designated photomicrographs for better visualization of immunopositive cells. Scale bar in represents 200 μm.<p><b>Copyright information:</b></p><p>Taken from "Detailed immunohistochemical characterization of temporal and spatial progression of Alzheimer's disease-related pathologies in male triple-transgenic mice"</p><p>http://www.biomedcentral.com/1471-2202/9/81</p><p>BMC Neuroscience 2008;9():81-81.</p><p>Published online 12 Aug 2008</p><p>PMCID:PMC2527610.</p><p>