Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice-5

cotreated with vehicle or dexamethasone (3 mg/kg) during the LPS (3 mg/kg) injection. All the mice were imaged at 0 and 5 h after LPS injection. (B) Quantification of luciferase activity (photons/sec) with the LivingImage software. Data presented were mean ± SE. (C) Dexamethasone inhibits hIL-1βP-driven luciferase expression during zymosan induced acute arthritis. Female cHS4I-hIL-1βP-Luc mice (n = 3/group) were cotreated with vehicle or dexamethasone (50 μg/mouse) during the administration of zymosan (300 μg/mouse). All the mice were imaged at 0 and 4 h after zymosan injection. (D) Quantification of luciferase activity (photons/sec) of the articular region of the acute arthritis mice with the LivingImage software. Data presented were mean ± SE. *** indicate significant differences at p < 0.001. p/s/cm/sr: photons/sec/cm/steradian.<p><b>Copyright information:</b></p><p>Taken from "Functional imaging of interleukin 1 beta expression in inflammatory process using bioluminescence imaging in transgenic mice"</p><p>http://www.biomedcentral.com/1471-2172/9/49</p><p>BMC Immunology 2008;9():49-49.</p><p>Published online 19 Aug 2008</p><p>PMCID:PMC2529264.</p><p>