Entral memory (CM) or effector memory (EM) cells. (B) Expression profile of genes differentially expressed in naive and memory-phenotype CD4 T cells sorted using the gates shown in (A). Each row represents an individual gene, and each column a different sample of naive, EM or CM CD4 T cells from seven healthy donors. Genes upregulated in memory-phenotype cells are shown in purple, and those upregulated in naive cells in green.<p><b>Copyright information:</b></p><p>Taken from "High-throughput gene expression profiling of memory differentiation in primary human T cells"</p><p>http://www.biomedcentral.com/1471-2172/9/44</p><p>BMC Immunology 2008;9():44-44.</p><p>Published online 1 Aug 2008</p><p>PMCID:PMC2529265.</p><p></p
<p>(A) HLA class II tetramer stained CD4-purified cells from LTBI donors. Tetramer<sup>+</sup> cells...
<p>mRNA was isolated from sorted CD62Lhi <i>early</i>M (30–45 days p.i.) and <i>late</i>M (8+ months...
International audienceAfter infection, many factors coordinate the population expansion and differen...
marker genes (lower panel) measured in sorted populations of naive (white bars) or memory-phenotype ...
Arker genes or control genes (grey symbols) between memory-phenotype and naive CD4 T cells. Values >...
Od T cells were calculated and the deviation of that data point from its corresponding mean were cal...
Background: The differentiation of naive T and B cells into memory lymphocytes is essential for immu...
Measured by the method in two different healthy donors. Rs and P value refer to Spearman correlation...
Memory T cells are heterogeneous in terms of their phenotype and functional properties. We investiga...
T cells are at the heart of the adaptive immune response. They mediate many important immunological ...
(A) Plot of the top significant enriched IPA pathways among T cell clusters, for significantly up- a...
Immune cells are highly heterogeneous and plastic with regard to gene expression and cell phenotype....
Upon infection, naive T cells proliferate and differentiate into highly specialized effector cells t...
Roups (with mostly upregulated genes and with mostly downregulated genes) according to their distinc...
T cell activation in response to antigenic stimulation is a complex process, involving changes in th...
<p>(A) HLA class II tetramer stained CD4-purified cells from LTBI donors. Tetramer<sup>+</sup> cells...
<p>mRNA was isolated from sorted CD62Lhi <i>early</i>M (30–45 days p.i.) and <i>late</i>M (8+ months...
International audienceAfter infection, many factors coordinate the population expansion and differen...
marker genes (lower panel) measured in sorted populations of naive (white bars) or memory-phenotype ...
Arker genes or control genes (grey symbols) between memory-phenotype and naive CD4 T cells. Values >...
Od T cells were calculated and the deviation of that data point from its corresponding mean were cal...
Background: The differentiation of naive T and B cells into memory lymphocytes is essential for immu...
Measured by the method in two different healthy donors. Rs and P value refer to Spearman correlation...
Memory T cells are heterogeneous in terms of their phenotype and functional properties. We investiga...
T cells are at the heart of the adaptive immune response. They mediate many important immunological ...
(A) Plot of the top significant enriched IPA pathways among T cell clusters, for significantly up- a...
Immune cells are highly heterogeneous and plastic with regard to gene expression and cell phenotype....
Upon infection, naive T cells proliferate and differentiate into highly specialized effector cells t...
Roups (with mostly upregulated genes and with mostly downregulated genes) according to their distinc...
T cell activation in response to antigenic stimulation is a complex process, involving changes in th...
<p>(A) HLA class II tetramer stained CD4-purified cells from LTBI donors. Tetramer<sup>+</sup> cells...
<p>mRNA was isolated from sorted CD62Lhi <i>early</i>M (30–45 days p.i.) and <i>late</i>M (8+ months...
International audienceAfter infection, many factors coordinate the population expansion and differen...