Neutrophil elastase reduces secretion of secretory leukoproteinase inhibitor (SLPI) by lung epithelial cells: role of charge of the proteinase-inhibitor complex-0

E y axis shows the average of the SLPI secreted in each condition as a percentage of the SLPI secreted by control cells (% SLPI release). Error bars represent standard error of the mean (SEM). N = 3–5 separate experiments for all except buffer control (N = 2). A dose-related reduction in SLPI supernatant concentration was seen with NE (statistically significant from 2.5 nM) (p = 0.006, one way ANOVA).<p><b>Copyright information:</b></p><p>Taken from "Neutrophil elastase reduces secretion of secretory leukoproteinase inhibitor (SLPI) by lung epithelial cells: role of charge of the proteinase-inhibitor complex"</p><p>http://respiratory-research.com/content/9/1/60</p><p>Respiratory Research 2008;9(1):60-60.</p><p>Published online 12 Aug 2008</p><p>PMCID:PMC2529288.</p><p>