Hallenged with saline or LPS i.p. A) Social exploratory behavior was measured before i.p. LPS injection and again 2, 4, 8, and 24 h later. Graph represents the mean ± SEM (n = 10). Means with * are significantly different (< 0.05) from saline controls and means with ‡ are significantly different from . In the same experiment, B) body weight and C) food intake were measured before i.p. LPS injection and again 2, 4, 8, and 24 h later. Bars represent the mean ± SEM (n = 10). Means with different letters (a, b, c, or d) are significantly different (< 0.05) from each other.<p><b>Copyright information:</b></p><p>Taken from "Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia"</p><p>Journal o...
Interactions between the immune and neuroendocrine systems result in sickness behaviors and activate...
Background Inflammation rapidly reorients motivational state, mood is impaired, pleasurable activit...
Fig. S1. The effect of Lipopolysaccharide (LPS) on apparent sickness, directly and via the mediators...
Hallenged with saline or LPS i.p. and sucrose preference was determined 24 to 39 h post LPS. Bars re...
Hallenged with either saline or LPS i.p and A) IL-1β, B) IL-6, and C) IDO mRNA levels were determine...
Day mice were challenged with saline or LPS i.p. and A) MHC II, B) TLR2, C) IL-1β, D) IL-6, and E) I...
Njected with saline or LPS i.p. IL-1β and IL-6 were determined in plasma collected 4 h later. There ...
Ined from supernatants collected 4 h later. B) BV-2 cells were pretreated with 0, 25, 50, 100, 200, ...
Ined from supernatants collected 4 h later. B) BV-2 cells were pretreated with 0, 25, 50, 100, 200, ...
Were challenged with saline or LPS i.p., microglia and macrophages were collected 24 h later and TLR...
<p>Mice were challenged with saline (control) or LPS or LPS combined with Dex or Dex+Yoh. (A) Social...
<p>The data is shown as means ± SEM. n = 8 for each group. ** P<0.01. compared with saline-injected ...
Minocycline has shown therapeutic promise in pre-clinical animal models and early phase clinical tri...
An immune component has been suggested to underlie the pathophysiology of psychiatric diseases, and ...
Neuroinflammation following lipopolysaccharide (LPS) administration induces locomotor deficits and a...
Interactions between the immune and neuroendocrine systems result in sickness behaviors and activate...
Background Inflammation rapidly reorients motivational state, mood is impaired, pleasurable activit...
Fig. S1. The effect of Lipopolysaccharide (LPS) on apparent sickness, directly and via the mediators...
Hallenged with saline or LPS i.p. and sucrose preference was determined 24 to 39 h post LPS. Bars re...
Hallenged with either saline or LPS i.p and A) IL-1β, B) IL-6, and C) IDO mRNA levels were determine...
Day mice were challenged with saline or LPS i.p. and A) MHC II, B) TLR2, C) IL-1β, D) IL-6, and E) I...
Njected with saline or LPS i.p. IL-1β and IL-6 were determined in plasma collected 4 h later. There ...
Ined from supernatants collected 4 h later. B) BV-2 cells were pretreated with 0, 25, 50, 100, 200, ...
Ined from supernatants collected 4 h later. B) BV-2 cells were pretreated with 0, 25, 50, 100, 200, ...
Were challenged with saline or LPS i.p., microglia and macrophages were collected 24 h later and TLR...
<p>Mice were challenged with saline (control) or LPS or LPS combined with Dex or Dex+Yoh. (A) Social...
<p>The data is shown as means ± SEM. n = 8 for each group. ** P<0.01. compared with saline-injected ...
Minocycline has shown therapeutic promise in pre-clinical animal models and early phase clinical tri...
An immune component has been suggested to underlie the pathophysiology of psychiatric diseases, and ...
Neuroinflammation following lipopolysaccharide (LPS) administration induces locomotor deficits and a...
Interactions between the immune and neuroendocrine systems result in sickness behaviors and activate...
Background Inflammation rapidly reorients motivational state, mood is impaired, pleasurable activit...
Fig. S1. The effect of Lipopolysaccharide (LPS) on apparent sickness, directly and via the mediators...