The orientation of the CTCF/H2A.Z pattern is correlated with the orientation of the CTCF binding motif.
- Fiona G. G. Nielsen (189346)
- Kasper Galschiøt Markus (189354)
- Rune Møllegaard Friborg (189363)
- Lene Monrad Favrholdt (189371)
- Hendrik G. Stunnenberg (142800)
- Martijn Huynen (189382)
Publication date
January 2012
DOIAbstract
<p>(a) Of the eleven zincfingers in CTCF, only four are required for strong binding. The orientation of the binding with respect to the CTCF motif was determined by Renda et al <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0028272#pone.0028272-Renda1" target="_blank">[23]</a>. (b) The dominant orientation of the CTCF/H2A.Z pattern with respect to the orientation of the underlying CTCF motif. (c) The CTCF motif as derived from motif detection in genome-wide CTCF peaks in the ChIP-seq dataset of Barski et al <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0028272#pone.0028272-Barski1" target="_blank">[6]</a>.</p
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