<i>Mfn-1</i> RNAi results in reduced brood size and abnormal gonad morphology.

<p>A) Progeny number was measured every day after L4 stage. The results represent five independent experiments with totally 30 worms measured respectively each day. The histogram represents average ± SD. B) Total brood size measured. Average brood size of l4440 RNAi worms is 290±20, while the brood size of <i>mfn-1</i> RNAi worms is 144±51, p<0.0001. Thirty brood sizes were measures respectively. C) Gonad images of 2-day old adults. Arrow indicates oocyte, scale bar = 30 µm.