Transport and metabolism in Caco-2 cells.
- Zenghui Teng (133526)
- Chengjun Yuan (188612)
- Feng Zhang (6548)
- Menglei Huan (133523)
- Weidong Cao (188616)
- Kangchu Li (188620)
- Jingyue Yang (188622)
- Dayong Cao (188624)
- Siyuan Zhou (133533)
- Qibing Mei (133534)
DOIAbstract
<p>Intracellular accumulation of polyphenol compounds and their metabolites, (a<sub>1</sub>) apigenin and metabolites, (a<sub>2</sub>) resveratrol and metabolites, (a<sub>3</sub>) emodin and metabolites, (a<sub>4</sub>) chrysophanol and metabolites. Transport of glucuronides and sulphates from different directions in Caco-2 cells (nmol/L• mg • protein), (b<sub>1</sub>) glucuronides from AP to BL, (b<sub>2</sub>) sulphates from AP to BL, (b<sub>3</sub>) glucuronides from BL to AP, (b<sub>4</sub>) sulphates from BL to AP. The effect of different inhibitors (100 µM verapamil,100 µM cyclosporine A, 50 µM phloridzin) on the transport of polyphenol compounds in Caco-2 cells; (c<sub>1</sub>) apigenin, (c<sub>2</sub>) resveratrol, (c<sub>3</sub>) e...
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