Effect of RU486 treatment on the expression of PLIN2.

<p>Expression of PLIN2 by real-time PCR in breast cancer T47D (A) and primary uterine leiomyoma cells (B). Serum-starved T47D or leiomyoma cells were stimulated with variable concentrations of RU486 (ranging from 10⁻⁹ to 10⁻⁵ M) or vehicle for 6 hours (C and D), or RU486 (10⁻⁶ M) or vehicle for 1, 3, 6, or 24 hours (E and F). PLIN2 mRNA levels were normalized to GAPDH expression. Results are reported as fold change compared with cells treated with vehicle only and represent the mean ± SEM of three independent experiments. Reference: star symbol, p<0.05 compared with vehicle treatment.